indeterminate cytology
Fine needle aspiration results that cannot definitively classify a thyroid nodule as benign or malignant.
Full Definition
Cytologic findings from thyroid fine needle aspiration that fall into Bethesda categories III (atypia of undetermined significance) or IV (follicular neoplasm). These results indicate cellular abnormalities that cannot be definitively classified as benign or malignant based on cytology alone. Indeterminate cytology often necessitates either repeat biopsy, molecular testing, or surgical excision for definitive diagnosis. The malignancy risk varies by specific category and institutional factors.
Usage
Usage note: Specify Bethesda category when known; distinguish from nondiagnostic specimens.
In Context
- "Indeterminate cytology results prompted consideration of molecular testing before surgical decision-making." — Clinical decision documentation
- "The thyroid nodule with indeterminate cytology was managed with diagnostic lobectomy." — Surgical indication