FLOT
Pronunciation: flot
Also written as: FLOT — fluorouracil, leucovorin, oxaliplatin, and docetaxel
Chemotherapy regimen combining fluorouracil, leucovorin, oxaliplatin, and docetaxel for gastric cancer treatment.
Full Definition
FLOT is a four-drug chemotherapy regimen consisting of fluorouracil (5-FU), leucovorin (folinic acid), oxaliplatin, and docetaxel (Taxotere). This regimen has become a standard perioperative treatment for locally advanced gastric and gastroesophageal junction adenocarcinomas, based on superior outcomes compared to earlier regimens. Editorial note: Always capitalize all letters; ensure proper context distinguishes from other combination regimens.
Usage
Usage note: All capitals; spell out component drugs on first use in formal documents.
In Context
- "The patient received four cycles of FLOT chemotherapy prior to gastrectomy." — Treatment plan documentation
- "FLOT demonstrated superior survival outcomes compared to ECF in the FLOT4-AIO trial." — Clinical trial analysis