Virchow's node
Pronunciation: VEER-khoff node
An enlarged left supraclavicular lymph node that may indicate metastatic gastric or abdominal cancer.
Full Definition
Virchow's node, also known as the sentinel node or Troisier's sign when palpable, is an enlarged left supraclavicular lymph node that serves as a clinical indicator of potential intra-abdominal malignancy, particularly gastric cancer. The anatomical basis involves lymphatic drainage from the abdomen through the thoracic duct, which terminates near the left supraclavicular region. Detection of this enlarged node often represents advanced disease with systemic spread and generally indicates poor prognosis. In gastrointestinal oncology, the presence of Virchow's node typically upstages the patient to metastatic disease, significantly altering treatment approach from curative to palliative intent.
Usage
Usage note: Use possessive form with apostrophe: 'Virchow's node.' Capitalize as an eponym.
In Context
- "Physical examination revealed a palpable Virchow's node, suggesting metastatic spread from the gastric primary." — Clinical examination note
- "CT imaging confirmed enlarged left supraclavicular lymphadenopathy consistent with Virchow's node." — Radiology report