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Technical
IVT
Adrenocorticotropic Hormone
Also written as: ACTH — Adrenocorticotropic Hormone
A pituitary hormone that stimulates cortisol production, used to evaluate adrenal function.
Full Definition
Adrenocorticotropic hormone (ACTH) is a 39-amino acid peptide hormone produced by the anterior pituitary gland that stimulates the adrenal cortex to produce cortisol and other glucocorticoids. ACTH secretion follows a circadian rhythm with peak levels in the early morning. ACTH testing is essential in differentiating primary adrenal insufficiency (Addison's disease) from secondary causes, and in evaluating Cushing's syndrome. The ACTH stimulation test assesses adrenal reserve function.
Usage
Usage note: ACTH is temperature-sensitive and requires special handling for accurate results.
In Context
- "Elevated ACTH with low cortisol confirmed primary adrenal insufficiency." — Endocrinology report
- "The adrenocorticotropic hormone stimulation test showed inadequate cortisol response." — Diagnostic procedure report
Also known as
ACTH
Corticotropin
Don't confuse with
Cortisol
Aldosterone