Aldosterone
Pronunciation: al-DOS-ter-own
A mineralocorticoid hormone that regulates sodium and potassium balance, measured in hypertension workup.
Full Definition
Aldosterone is a steroid hormone produced by the zona glomerulosa of the adrenal cortex that plays a crucial role in electrolyte and fluid balance by promoting sodium retention and potassium excretion in the kidneys. Aldosterone secretion is primarily regulated by the renin-angiotensin-aldosterone system and serum potassium levels. Aldosterone measurements are essential in evaluating primary aldosteronism (Conn's syndrome), a common cause of secondary hypertension, and in assessing various forms of adrenal dysfunction.
Usage
Usage note: Specify plasma aldosterone concentration (PAC) when reporting quantitative results.
In Context
- "Plasma aldosterone concentration was markedly elevated at 850 pmol/L in the hypertensive patient." — Hypertension workup report
- "Aldosterone suppression testing confirmed the diagnosis of primary aldosteronism." — Endocrinology evaluation