Professional
Technical
IVT
Aldosterone-to-Renin Ratio
Also written as: ARR
A screening test for primary aldosteronism, the most common cause of secondary hypertension.
Full Definition
The aldosterone-to-renin ratio is calculated by dividing plasma aldosterone concentration by plasma renin activity or direct renin concentration. An elevated ARR (typically >20-30) suggests primary aldosteronism, where aldosterone production is autonomous and renin is suppressed. This condition causes hypertension and hypokalemia. The test requires specific patient preparation including medication washout and dietary considerations, as many factors affect both aldosterone and renin levels.
Usage
Usage note: Specify medication washout requirements; note collection position and timing.
In Context
- "An ARR of 45 ng/dL per ng/mL/h indicates probable primary aldosteronism requiring confirmatory testing." — Hypertension workup
- "Patient must discontinue spironolactone for 6 weeks before ARR testing for accuracy." — Clinical protocol
Also known as
ARR
Plasma Aldosterone-to-Renin Ratio
Don't confuse with
Aldosterone Level
Renin Level
Cortisol-to-Cortisone Ratio