PPROM
Also written as: PPROM — preterm premature rupture of membranes
Preterm premature rupture of membranes occurring before 37 weeks gestation and prior to onset of labor.
Full Definition
Preterm premature rupture of membranes (PPROM) is defined as rupture of fetal membranes before 37 weeks of gestation and prior to the onset of labor. This complication affects 2-4% of all pregnancies and accounts for approximately one-third of preterm births. PPROM is associated with significant maternal and neonatal morbidity, including chorioamnionitis, placental abruption, cord prolapse, and neonatal complications related to prematurity. Management involves careful assessment of gestational age, fetal lung maturity, signs of infection, and consideration of expectant management versus delivery. Latency antibiotics and corticosteroids for fetal lung maturation are standard interventions.
Usage
Usage note: Distinguish from term PROM (>37 weeks) and specify gestational age when editing.
In Context
- "The patient presented at 32 weeks with PPROM confirmed by positive pooling, nitrazine, and ferning tests." — Emergency department obstetric evaluation
- "PPROM management included administration of betamethasone and ampicillin pending delivery planning." — Maternal fetal medicine treatment plan