surfactant replacement therapy
A treatment involving the administration of artificial or natural surfactant to premature infants with respiratory distress syndrome.
Full Definition
Surfactant replacement therapy is a critical intervention for premature infants with respiratory distress syndrome (RDS) who lack adequate natural surfactant production. The therapy involves the intratracheal administration of exogenous surfactant, either synthetic or derived from animal sources, directly into the lungs. This treatment helps reduce surface tension in the alveoli, improves lung compliance, and enhances oxygenation. Surfactant can be given prophylactically immediately after birth or as rescue therapy when RDS develops. The timing and type of surfactant used can significantly impact outcomes in premature infants.
Usage
Usage note: Specify whether prophylactic or rescue therapy and the specific surfactant preparation used.
In Context
- "The extremely premature infant received prophylactic surfactant replacement therapy immediately after delivery." — Delivery room documentation
- "Surfactant replacement therapy significantly improved the infant's oxygenation and reduced ventilator requirements." — Progress note