TORCH infections
Pronunciation: torch
Also written as: TORCH — Toxoplasmosis, Other, Rubella, Cytomegalovirus, Herpes
Group of congenital infections that can cause significant morbidity in newborns when transmitted from mother to fetus.
Full Definition
TORCH is an acronym representing a group of infectious agents that can cause congenital infections with similar clinical presentations in newborns. The classic TORCH infections include Toxoplasmosis, Other agents (including syphilis, varicella, parvovirus B19), Rubella, Cytomegalovirus (CMV), and Herpes simplex virus. These pathogens can cross the placenta during pregnancy or infect the infant during delivery, potentially causing intrauterine growth restriction, developmental delays, hearing loss, vision problems, and other serious complications. Early recognition and testing are crucial for appropriate management and family counseling.
Usage
Usage note: The 'O' in TORCH now commonly includes multiple agents. Some references use STORCH with 'S' for syphilis. Always specify which agents are being tested.
In Context
- "A TORCH workup was ordered due to microcephaly and growth restriction." — Diagnostic evaluation
- "The infant's presentation was consistent with a congenital TORCH infection." — Consultation note