Corpus Callosum Involvement
Tumor extension into or through the corpus callosum, often indicating aggressive behavior and poor prognosis.
Full Definition
Corpus callosum involvement refers to tumor extension into or through the corpus callosum, the large white matter tract connecting the cerebral hemispheres. This finding is particularly significant in gliomas as it often indicates aggressive tumor behavior and may preclude complete surgical resection. The classic appearance of glioblastoma crossing the corpus callosum creates a 'butterfly glioma' pattern on imaging. In clinical documentation, corpus callosum involvement carries important prognostic implications and influences treatment planning. Editors should understand that this anatomical involvement often correlates with higher tumor grade and more aggressive clinical course.
Usage
Usage note: Often associated with butterfly glioma appearance; indicates poor prognosis in most cases.
In Context
- "MRI demonstrated corpus callosum involvement with bilateral frontal lobe extension." — Imaging report
- "The presence of corpus callosum involvement suggests a high-grade lesion requiring aggressive treatment." — Oncology consultation