Cortical Dysplasia
Developmental malformation of cerebral cortex that may be associated with brain tumors or seizures.
Full Definition
Cortical dysplasia refers to abnormal development and organization of the cerebral cortex during embryonic and fetal brain development. This malformation can present as isolated findings or in association with brain tumors, particularly low-grade gliomas and gangliogliomas. In neuro-oncology practice, cortical dysplasia may complicate surgical planning and seizure management in tumor patients. The condition is classified into different subtypes based on histological features and clinical presentation. Editors should understand that cortical dysplasia can both predispose to tumor development and coexist with neoplastic lesions, making accurate documentation crucial for treatment planning.
Usage
Usage note: May coexist with tumors; important for surgical planning and seizure management.
In Context
- "Histopathology revealed focal cortical dysplasia adjacent to the resected tumor specimen." — Pathology report
- "The epileptogenic zone encompassed both the tumor and surrounding cortical dysplasia." — Epilepsy surgery evaluation