brain tumor recurrence
Return of tumor growth after initial treatment, requiring ongoing monitoring and potential re-intervention.
Full Definition
Brain tumor recurrence refers to the regrowth or reappearance of neoplastic tissue after initial surgical resection, radiation therapy, or chemotherapy. Recurrence can be local (at the original site), distant (in other brain regions), or leptomeningeal (involving the cerebrospinal fluid spaces). The pattern and timing of recurrence varies by tumor type, with high-grade gliomas typically recurring within months to years, while lower-grade tumors may recur after longer intervals. Detection requires serial imaging and may necessitate repeat surgery, additional radiation, or systemic therapy.
Usage
Usage note: Distinguish from pseudoprogression, which mimics recurrence on imaging but represents treatment effect.
In Context
- "MRI surveillance detected brain tumor recurrence eighteen months after initial resection." — Follow-up imaging report
- "The multidisciplinary team discussed treatment options for brain tumor recurrence." — Tumor board documentation