encephalocele
Pronunciation: en-SEF-ah-loh-seel
Congenital neural tube defect resulting in herniation of brain tissue through a skull opening.
Full Definition
A rare congenital malformation characterized by the protrusion of brain tissue and meninges through a defect in the skull, most commonly occurring in the occipital region. Encephaloceles result from failure of neural tube closure during embryonic development and may contain varying amounts of brain tissue, cerebrospinal fluid, and blood vessels. The condition requires careful imaging assessment to determine the contents of the herniated sac and surgical planning for repair, with outcomes depending on the amount and type of neural tissue involved.
Usage
Usage note: Distinguish from meningocele (meninges only) and ensure accurate spelling (not 'encephalocele').
In Context
- "The newborn presented with a large occipital encephalocele requiring urgent neurosurgical evaluation." — pediatric consultation
- "MRI imaging revealed functional brain tissue within the encephalocele sac, complicating surgical planning." — radiology report