CNS-PRES
Pronunciation: C-N-S PREEZ
Also written as: CNS-PRES — Central Nervous System Posterior Reversible Encephalopathy Syndrome
Central nervous system posterior reversible encephalopathy syndrome, characterized by vasogenic edema and neurological symptoms.
Full Definition
CNS-PRES (Central Nervous System Posterior Reversible Encephalopathy Syndrome) is a clinico-radiological syndrome characterized by acute neurological symptoms including seizures, altered mental status, visual disturbances, and headache, associated with characteristic bilateral parieto-occipital white matter edema on neuroimaging. PRES typically occurs in the setting of hypertension, immunosuppressive therapy, renal disease, or autoimmune conditions. While often reversible with appropriate treatment, PRES can have permanent sequelae if not promptly recognized and managed. The syndrome represents an important differential diagnosis in patients with acute neurological deterioration.
Usage
Usage note: Can be abbreviated as PRES when CNS context is clear. Always capitalize the acronym.
In Context
- "The patient developed CNS-PRES following initiation of high-dose immunosuppressive therapy." — Case report
- "Neuroimaging findings were consistent with CNS-PRES, showing bilateral posterior white matter edema." — Radiology report