lymphocytic pleocytosis
Pronunciation: lim-fo-SIT-ik plee-oh-sy-TOH-sis
Elevated lymphocyte count in cerebrospinal fluid indicating CNS inflammation in neuroimmunological disorders.
Full Definition
Lymphocytic pleocytosis refers to an increased number of lymphocytes in the cerebrospinal fluid, typically defined as more than 5 lymphocytes per microliter in adults. This finding indicates inflammatory activity within the central nervous system and is commonly seen in neuroimmunological conditions such as multiple sclerosis, autoimmune encephalitis, and viral encephalitis. The degree of pleocytosis can vary widely, from mild elevation to hundreds of cells per microliter, depending on the underlying condition and disease activity. CSF analysis showing lymphocytic pleocytosis, along with other parameters like protein elevation and oligoclonal bands, helps support the diagnosis of inflammatory CNS disorders and guides treatment decisions.
Usage
Usage note: Pleocytosis specifically refers to increased white blood cells; lymphocytic specifies the cell type.
In Context
- "Lumbar puncture revealed lymphocytic pleocytosis with 25 white blood cells per microliter." — CSF analysis report
- "The presence of lymphocytic pleocytosis supported the diagnosis of autoimmune encephalitis." — Clinical assessment