Cordotomy
A neurosurgical ablation procedure that interrupts ascending pain pathways in the spinal cord, contrasting with neuromodulation approaches.
Full Definition
Cordotomy is a neurosurgical ablation procedure that involves interrupting ascending pain pathways in the spinal cord, specifically targeting the spinothalamic tract. Unlike reversible neuromodulation techniques, cordotomy creates permanent lesions to disrupt pain signal transmission from the affected body regions to the brain. The procedure can be performed through open surgical approaches or using stereotactic radiofrequency techniques. While effective for certain pain conditions, particularly cancer-related pain, cordotomy carries risks including weakness, sensory loss, and respiratory complications. In the context of neuromodulation, cordotomy represents an alternative ablative approach when reversible stimulation techniques have failed or are not suitable.
Usage
Usage note: Distinguish clearly from reversible neuromodulation procedures.
In Context
- "Cordotomy was considered as a last resort after spinal cord stimulation failed to provide adequate cancer pain relief." — Multidisciplinary team discussion
- "The irreversible nature of cordotomy contrasts sharply with adjustable neuromodulation therapies." — Treatment comparison