Oncology Informatics Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
COSMIC COSMIC
The Catalogue of Somatic Mutations in Cancer, a comprehensive database of cancer-associated genetic variants.
pharmacogenomics
The study of how genetic variants influence individual responses to cancer therapeutics.
precision medicine knowledge base
Curated database containing genomic variants, drug associations, and clinical evidence to support personalized cancer tr...
precision oncology dashboard
An integrated clinical interface that presents genomic test results, treatment options, and clinical decision support to...
precision oncology data model
Structured framework for organizing and representing genomic, clinical, and treatment data to support personalized cance...
precision oncology workflow
A systematic process integrating molecular testing with clinical data to guide personalized cancer treatment decisions.
progression-free survival
Clinical trial endpoint measuring time from treatment initiation to disease progression or death, whichever occurs first...
RECIST
Response Evaluation Criteria in Solid Tumors - standardized criteria for measuring tumor response to treatment in cancer...
REDCap
Research Electronic Data Capture, a web-based application designed for building and managing online surveys and database...
RWE
Real-World Evidence derived from analysis of real-world data to support regulatory decisions and clinical practice in on...
SDTM
Study Data Tabulation Model, a CDISC standard that defines the structure and content requirements for clinical trial dat...
SEER
Surveillance, Epidemiology, and End Results - NCI's premier cancer surveillance program providing population-based data.
SNOMED CT
Comprehensive clinical terminology system used for standardized coding of oncology diagnoses, procedures, and clinical f...
somatic variant calling
The computational process of identifying genetic mutations present only in tumor tissue, not inherited germline DNA.
synthetic control arm
Computationally generated control group created from historical patient data to serve as a comparison in clinical trials...
synthetic patient cohort generation
Computational process creating artificial cancer patient datasets that preserve statistical properties while protecting...
TNM staging
Standardized cancer staging system using Tumor size, Node involvement, and Metastasis status to classify disease extent.
treatment response assessment protocol
Standardized methodology for systematically evaluating cancer treatment effectiveness using defined imaging and clinical...
tumor board EHR integration
Technical infrastructure connecting multidisciplinary cancer case review systems with electronic health record platforms...
tumor board management system
Software platform designed to organize, schedule, and document multidisciplinary tumor board meetings and case presentat...
tumor heterogeneity
The genetic and phenotypic diversity present within a single tumor or between tumors in the same patient.
tumor immune microenvironment
The complex cellular and molecular ecosystem surrounding cancer cells that influences immune response and therapeutic ou...
tumor mutational burden
A quantitative measure of the total number of mutations present in a tumor genome.
tumor purity
The percentage of cancer cells present in a tumor tissue sample.
tumor registry software
Specialized information systems designed to collect, store, and manage comprehensive data about cancer cases for populat...