acrodermatitis enteropathica
Pronunciation: ak-roh-dur-muh-TY-tis en-ter-oh-PATH-ik-uh
A rare genetic disorder in infants causing zinc deficiency with characteristic skin lesions around body orifices.
Full Definition
Acrodermatitis enteropathica is an autosomal recessive disorder affecting zinc absorption, primarily manifesting in infancy with distinctive perioral, perianal, and acral dermatitis. The condition presents with vesiculobullous and eczematous lesions that can be mistaken for other inflammatory conditions. Early recognition is crucial as zinc supplementation provides complete resolution. Medical writers must distinguish this from similar-appearing nutritional deficiencies and infectious dermatoses in pediatric contexts.
Usage
Usage note: Always lowercase except when beginning a sentence. Hyphenate the compound term.
In Context
- "The infant's perioral erosions and failure to thrive suggested acrodermatitis enteropathica rather than atopic dermatitis." — case report
- "Prompt zinc supplementation in acrodermatitis enteropathica prevents long-term complications." — treatment guideline