acropustulosis of infancy
Pronunciation: ak-ro-pus-tu-LO-sis
Also written as: AIP — acropustulosis of infancy
A benign, recurrent vesiculopustular eruption affecting the palms and soles of infants and young children.
Full Definition
Acropustulosis of infancy is a rare, benign condition characterized by recurrent crops of intensely pruritic vesicles and pustules on the palms, soles, and lateral aspects of the hands and feet. The condition typically presents within the first few months of life and follows a cyclical pattern with flares lasting 1-2 weeks followed by remission periods of several weeks to months. The lesions are sterile and cultures are negative for bacteria or fungi. The condition is self-limiting and usually resolves by 2-3 years of age, though symptomatic treatment with topical corticosteroids may be needed for severe itching.
Usage
Usage note: Do not hyphenate; emphasize the acral (hands and feet) distribution in documentation.
In Context
- "The cyclical nature of the palmoplantar pustules was consistent with acropustulosis of infancy." — Differential diagnosis note
- "Scabies was ruled out before confirming the diagnosis of acropustulosis of infancy." — Clinical assessment