spitz nevus
A benign melanocytic lesion in children that may resemble melanoma histologically.
Full Definition
Spitz nevus is a benign melanocytic lesion that predominantly affects children and adolescents, typically presenting as a pink, red, or pigmented nodule on the face or extremities. These lesions are histologically characterized by epithelioid and spindle-shaped melanocytes and may show features that overlap with melanoma, making diagnosis challenging. Due to their atypical appearance and potential for misdiagnosis, Spitz nevi often require excisional biopsy and expert dermatopathologic evaluation. Most are completely benign, but rare variants may have uncertain malignant potential.
Usage
Usage note: Capitalize 'Spitz' as it's an eponym; emphasize need for expert histologic evaluation in documentation.
In Context
- "Excisional biopsy of the Spitz nevus was recommended due to its atypical clinical appearance." — Pediatric dermatology referral
- "The dermatopathologist confirmed the diagnosis of Spitz nevus with negative margins." — Pathology report review