TEWL
Pronunciation: spell out: T-E-W-L
Also written as: TEWL — Transepidermal water loss
Abbreviation for transepidermal water loss; a measure of epidermal barrier integrity widely used in paediatric dermatology research.
Full Definition
TEWL is the standard abbreviation for transepidermal water loss, the rate at which water passively diffuses and evaporates through the epidermal barrier. It is a core outcome measure in paediatric dermatology studies, particularly those investigating barrier-dysfunction disorders such as atopic dermatitis, neonatal skin conditions, and ichthyosis. TEWL values are typically reported in g/m²/h. Editors should ensure it is expanded on first use and that the acronym is not confused with 'perspiration,' which involves active sweat-gland secretion.
Usage
Usage note: Must be defined at first use. Do not italicise in running text.
In Context
- "TEWL values exceeding 15 g/m²/h were considered indicative of significant barrier impairment in this study." — Methods section, paediatric dermatology journal article
- "The table summarised TEWL, stratum corneum hydration, and pH at each follow-up visit." — Clinical trial data table