anti-Müllerian hormone
A hormone produced by developing gonads that indicates ovarian reserve in girls and testicular function in boys.
Full Definition
Anti-Müllerian hormone (AMH) is a glycoprotein produced by granulosa cells in ovarian follicles and Sertoli cells in the testes. In pediatric endocrinology, AMH serves as a valuable biomarker for assessing gonadal function and development. In girls, AMH levels reflect ovarian reserve and can help evaluate conditions like polycystic ovary syndrome or premature ovarian insufficiency. In boys, AMH indicates Sertoli cell function and can aid in the evaluation of disorders of sexual development. AMH levels vary significantly with age and pubertal status, requiring age-appropriate reference ranges for interpretation.
Usage
Usage note: May be abbreviated as AMH or MIS; hyphenate 'anti-Müllerian' when spelled out.
In Context
- "The patient's anti-Müllerian hormone level was elevated, consistent with polycystic ovary syndrome." — Laboratory interpretation
- "Undetectable anti-Müllerian hormone in this prepubertal boy suggested absent testicular tissue." — Endocrine evaluation