gonadotropin
Pronunciation: goh-nad-oh-TROH-pin
Hormones that stimulate the gonads (ovaries and testes), primarily FSH and LH, crucial for pubertal development.
Full Definition
Gonadotropins are glycoprotein hormones secreted by the anterior pituitary gland that regulate reproductive function by stimulating the gonads. The two main gonadotropins are follicle-stimulating hormone (FSH) and luteinizing hormone (LH). In pediatric endocrinology, gonadotropin levels are essential markers for assessing pubertal development and diagnosing disorders of sexual maturation. During puberty, increased gonadotropin secretion triggers the production of sex hormones (testosterone in males, estrogen in females) and the development of secondary sexual characteristics. Abnormal gonadotropin levels can indicate various conditions including hypogonadotropic hypogonadism, gonadal dysgenesis, or central precocious puberty.
Usage
Usage note: Note the spelling variation 'gonadotrophin' in British English; both are acceptable.
In Context
- "Elevated gonadotropin levels confirmed the diagnosis of central precocious puberty." — Laboratory report
- "The patient's low gonadotropin levels suggested hypogonadotropic hypogonadism." — Endocrine evaluation