hypopituitarism
Decreased production of one or more anterior pituitary hormones, often causing growth retardation and delayed puberty in children.
Full Definition
Hypopituitarism refers to the diminished or absent secretion of one or more hormones from the anterior pituitary gland. In pediatric endocrinology, this condition commonly presents with growth hormone deficiency leading to short stature, but may also involve deficiencies in thyroid-stimulating hormone, adrenocorticotropic hormone, or gonadotropins. The condition can be congenital or acquired through trauma, tumors, or infections. Early recognition and treatment are crucial for optimizing growth potential and preventing long-term complications.
Usage
Usage note: Distinguished from specific hormone deficiencies by involving multiple pituitary axes.
In Context
- "The patient's growth chart and laboratory findings were consistent with hypopituitarism secondary to cranial irradiation." — Clinical report
- "MRI imaging revealed a small pituitary gland, supporting the diagnosis of congenital hypopituitarism." — Radiology report