aplastic anemia
Rare blood disorder where bone marrow fails to produce adequate blood cells in children.
Full Definition
Aplastic anemia is a serious blood disorder characterized by bone marrow failure resulting in decreased production of red blood cells, white blood cells, and platelets. In pediatric patients, this condition can be inherited (such as Fanconi anemia) or acquired through viral infections, medications, or unknown causes. The condition leads to fatigue, increased infection risk, and bleeding problems, often requiring intensive treatment including immunosuppressive therapy or bone marrow transplantation.
Usage
Usage note: Two words, no hyphenation. Distinguish from aplastic crisis (temporary cessation of red cell production).
In Context
- "Bone marrow biopsy confirmed severe aplastic anemia requiring immediate treatment." — Pathology report
- "The patient with aplastic anemia was evaluated for hematopoietic stem cell transplantation." — Transplant consultation