chelation therapy

Full Definition

Chelation therapy involves the use of specific medications to bind and remove excess iron from the body in patients who develop iron overload from repeated blood transfusions. In pediatric hematology, this therapy is essential for children with thalassemia, sickle cell disease, or other conditions requiring chronic transfusions. Iron chelating agents such as deferasirox or deferoxamine prevent iron deposition in vital organs like the heart and liver, reducing long-term complications.

Usage

Usage note: Two words. May be modified as 'iron chelation therapy' for specificity.

In Context

• "The patient began chelation therapy after developing iron overload from multiple transfusions." — Treatment plan
• "Compliance with chelation therapy is crucial for preventing cardiac complications in thalassemia patients." — Patient counseling note