hemolytic anemia
Anemia caused by premature destruction of red blood cells, common in pediatric genetic disorders.
Full Definition
Hemolytic anemia occurs when red blood cells are destroyed faster than they can be replaced by the bone marrow, leading to anemia and often jaundice. In children, this can be caused by inherited conditions like sickle cell disease, hereditary spherocytosis, or G6PD deficiency, or acquired causes such as autoimmune disorders or infections. Laboratory findings typically include elevated bilirubin, decreased haptoglobin, and increased reticulocyte count as the body attempts to compensate.
Usage
Usage note: Two words, no hyphenation. Specify underlying cause when known (e.g., 'sickle cell hemolytic anemia').
In Context
- "Laboratory results confirmed hemolytic anemia with elevated LDH and low haptoglobin levels." — Diagnostic workup
- "The child's hemolytic anemia was attributed to hereditary spherocytosis based on family history and osmotic fragility testing." — Genetics consultation