splenomegaly
Pronunciation: splee-no-MEG-ah-lee
Enlarged spleen commonly seen in pediatric blood disorders requiring careful monitoring.
Full Definition
Splenomegaly refers to abnormal enlargement of the spleen beyond normal size parameters for age. In pediatric hematology, splenomegaly is frequently observed in conditions such as sickle cell disease, thalassemia, leukemia, and hereditary spherocytosis. The enlarged spleen may cause pain, early satiety, and increased risk of splenic sequestration or rupture, requiring regular monitoring through physical examination and imaging studies.
Usage
Usage note: Single word, no hyphenation. Distinguish from hepatomegaly (enlarged liver).
In Context
- "Physical examination revealed significant splenomegaly extending 4 cm below the left costal margin." — Clinical examination note
- "Progressive splenomegaly in this thalassemia patient may require splenectomy consideration." — Hematology consultation