cerebrospinal fluid pleocytosis
Pronunciation: ser-ee-broh-SPY-nal FLOO-id plee-oh-sy-TOH-sis
Abnormal increase in white blood cells within cerebrospinal fluid, indicating central nervous system inflammation or infection.
Full Definition
Cerebrospinal fluid pleocytosis refers to an elevated white blood cell count in the cerebrospinal fluid, typically defined as >5 cells/μL in children beyond the neonatal period. This finding suggests inflammation of the central nervous system and is commonly seen in viral or bacterial meningitis, encephalitis, or other inflammatory conditions. The predominant cell type (lymphocytic vs neutrophilic) can provide diagnostic clues about the underlying etiology. Editors should note this term is often abbreviated in clinical documentation and requires careful attention to spelling.
Usage
Usage note: Often abbreviated as CSF pleocytosis in clinical notes; maintain consistency within documents.
In Context
- "The lumbar puncture revealed cerebrospinal fluid pleocytosis with 150 white blood cells per microliter." — Hospital discharge summary
- "Mild cerebrospinal fluid pleocytosis was noted, consistent with viral meningitis." — Pediatric neurology consultation