nephrocalcinosis
Pronunciation: nef-roh-kal-sin-OH-sis
Calcium deposition within the kidney parenchyma, commonly affecting the medullary pyramids in pediatric patients.
Full Definition
Nephrocalcinosis refers to the deposition of calcium salts within the kidney tissue, most commonly calcium phosphate or calcium oxalate. In children, this condition often results from metabolic disorders, medications, or genetic conditions affecting calcium handling. Unlike nephrolithiasis (kidney stones), nephrocalcinosis involves calcium deposits within the kidney tissue itself and can lead to progressive renal dysfunction.
Usage
Usage note: Distinguish from nephrolithiasis in clinical documentation.
In Context
- "Ultrasound revealed bilateral nephrocalcinosis in this patient with primary hyperoxaluria." — Radiology report
- "Progressive nephrocalcinosis was noted on follow-up imaging after furosemide therapy." — Clinical follow-up note