Professional
Technical
IVT
chloroma
Pronunciation: KLOR-oh-mah
A solid tumor mass composed of myeloid cells, also known as granulocytic sarcoma or myeloid sarcoma.
Full Definition
Chloroma, also called granulocytic sarcoma or myeloid sarcoma, is an extramedullary tumor composed of immature granulocytes. The term 'chloroma' derives from the characteristic greenish color caused by myeloperoxidase enzyme in the malignant cells. These tumors can occur anywhere in the body but commonly affect the orbits, central nervous system, and soft tissues in pediatric patients with acute myeloid leukemia.
Usage
Usage note: Preferred term is 'myeloid sarcoma' in current literature, though 'chloroma' remains widely used.
In Context
- "The orbital chloroma was initially misdiagnosed as rhabdomyosarcoma before flow cytometry confirmed myeloid lineage." — Pathology report
- "Chloroma may precede bone marrow involvement in pediatric AML by several months." — Clinical guidelines
Also known as
granulocytic sarcoma
myeloid sarcoma
extramedullary myeloid tumor
Don't confuse with
lymphoma
soft tissue sarcoma