induction therapy
The initial phase of cancer treatment designed to achieve complete remission by rapidly reducing tumor burden.
Full Definition
Induction therapy represents the first and most intensive phase of pediatric cancer treatment protocols. It typically involves high-dose chemotherapy combinations administered over several weeks to months with the primary goal of achieving complete remission. In pediatric oncology, induction regimens are carefully designed to balance maximum anti-tumor efficacy with acceptable toxicity profiles for developing children. Success is measured by achieving morphologic remission, typically defined as less than 5% blast cells in bone marrow for hematologic malignancies.
Usage
Usage note: Always specify the malignancy type when discussing induction protocols, as regimens vary significantly between cancer types.
In Context
- "The patient completed induction therapy with excellent tolerance and achieved morphologic remission." — Treatment summary report
- "Modify the induction therapy dosing based on the child's body surface area and organ function." — Protocol amendment