mucositis
Pronunciation: myoo-koh-SYE-tis
Inflammation and ulceration of mucous membranes, commonly occurring as a side effect of chemotherapy and radiation therapy.
Full Definition
Mucositis is a common and potentially debilitating side effect of cancer treatment characterized by inflammation, erythema, and ulceration of the mucous membranes lining the digestive tract. In pediatric oncology, oral mucositis is particularly problematic as it can lead to severe pain, difficulty eating and swallowing, increased risk of infection, and treatment delays. The condition typically develops 5-10 days after chemotherapy initiation and can persist for 1-2 weeks. Severity is often graded using standardized scales such as the WHO or CTCAE criteria. Management includes supportive care with pain control, nutritional support, infection prevention, and specific interventions such as oral cryotherapy, low-level laser therapy, or protective agents like sucralfate.
Usage
Usage note: Distinguish from specific infections like thrush; severity grading is important for documentation and treatment decisions.
In Context
- "Grade 3 mucositis required modification of the chemotherapy regimen and parenteral nutrition." — Supportive care consultation
- "Preventive oral care protocols were implemented to minimize mucositis risk." — Nursing care plan