Intermediate
Technical
In the Industry Vocabulary Test
Wilms tumor
A kidney cancer primarily affecting children, also called nephroblastoma.
Full Definition
Wilms tumor, also known as nephroblastoma, is the most common primary renal malignancy in children, typically occurring between ages 2-5 years. It accounts for approximately 5% of childhood cancers and can be associated with genetic syndromes such as WAGR or Beckwith-Wiedemann syndrome. The tumor staging follows the National Wilms Tumor Study Group (NWTSG) or International Society of Paediatric Oncology (SIOP) protocols. Treatment approach may involve pre-operative chemotherapy depending on the staging system used.
Usage
Usage note: May be capitalized as it derives from the physician's name.
In Context
- "The patient presented with a unilateral Wilms tumor without anaplastic features." — Surgical consultation note
- "Bilateral Wilms tumor requires nephron-sparing surgery when possible." — Treatment guideline
Also known as
nephroblastoma
Don't confuse with
clear cell sarcoma of kidney
rhabdoid tumor of kidney