lipodystrophy
Pronunciation: LIP-oh-dis-truh-fee
Loss of subcutaneous fat tissue, a potential complication of juvenile dermatomyositis or calcinosis.
Full Definition
Lipodystrophy in pediatric rheumatology refers to the partial or complete loss of subcutaneous fat tissue, most commonly associated with juvenile dermatomyositis. This complication can be localized to areas of previous inflammation or calcinosis, or may be more generalized. Lipodystrophy can result in significant cosmetic concerns and may indicate more severe or chronic disease. It can also be associated with metabolic complications including insulin resistance and dyslipidemia.
Usage
Usage note: Specify whether localized or generalized when documenting findings.
In Context
- "Focal lipodystrophy developed at the site of previous calcinosis deposits." — Long-term follow-up assessment
- "Generalized lipodystrophy was noted as a late complication of severe juvenile dermatomyositis." — Complications documentation