Professional
Technical
IVT
polyarticular RF-positive
A subtype of juvenile idiopathic arthritis affecting five or more joints with positive rheumatoid factor testing.
Full Definition
Polyarticular RF-positive JIA is a distinct subtype that affects five or more joints within the first six months of disease onset and shows positive rheumatoid factor serology. This form closely resembles adult rheumatoid arthritis and typically affects adolescent girls. It carries a more aggressive prognosis with greater risk of joint erosion and functional disability compared to seronegative forms.
Usage
Usage note: Always specify RF status when discussing polyarticular JIA subtypes.
In Context
- "The patient's polyarticular RF-positive presentation warranted aggressive immunosuppressive therapy." — Clinical assessment report
- "Differential diagnosis included polyarticular RF-positive JIA versus early-onset adult rheumatoid arthritis." — Consultation note
Also known as
polyarticular RF+ JIA
seropositive polyarticular JIA
Contrasted with
polyarticular RF-negative
oligoarticular JIA
Don't confuse with
polyarticular RF-negative
adult rheumatoid arthritis