Raynaud's phenomenon
Pronunciation: ray-NOHZ
Vasospastic disorder causing color changes in digits in response to cold or stress.
Full Definition
Raynaud's phenomenon is a vasospastic disorder characterized by episodic color changes in the fingers and toes in response to cold exposure or emotional stress. The classic triphasic color change involves initial pallor (white) due to vasospasm, followed by cyanosis (blue) from deoxygenation, and finally erythema (red) during reperfusion. In pediatric rheumatology, Raynaud's phenomenon may be primary (idiopathic) or secondary to underlying connective tissue diseases such as juvenile systemic sclerosis or mixed connective tissue disease. Secondary forms often present with more severe symptoms and may be associated with digital ulcerations or tissue loss.
Usage
Usage note: Named after Maurice Raynaud; use apostrophe + s in possessive form.
In Context
- "The patient's Raynaud's phenomenon improved significantly with calcium channel blocker therapy." — Treatment response documentation
- "Nailfold capillaroscopy revealed abnormal findings suggestive of secondary Raynaud's phenomenon." — Diagnostic evaluation