renal dysplasia
Abnormal kidney development characterized by disorganized tissue containing cysts and primitive structures.
Full Definition
Renal dysplasia is a congenital condition where normal kidney development is disrupted, resulting in abnormal tissue architecture with cystic spaces, primitive ducts, and sometimes cartilage. This condition can affect one or both kidneys and ranges from mild focal areas to complete replacement of normal kidney tissue. In pediatric urology, it's often associated with severe vesicoureteral reflux or obstructive uropathy and may require surgical intervention or long-term monitoring.
Usage
Usage note: Often hyphenated when used as a compound modifier (renal-dysplasia changes).
In Context
- "The prenatal ultrasound revealed severe renal dysplasia with multiple cysts replacing normal parenchyma." — Prenatal consultation report
- "Histopathologic examination confirmed renal dysplasia with primitive tubular structures and mesenchymal tissue." — Surgical pathology report