PPROM
Pronunciation: PEE-prom
Also written as: PPROM — Preterm Premature Rupture of Membranes
Rupture of fetal membranes before 37 weeks gestation and before the onset of labor.
Full Definition
Preterm Premature Rupture of Membranes (PPROM) is the spontaneous rupture of the chorioamniotic membranes before 37 weeks of gestation and before the onset of labor. This condition complicates 2-4% of all pregnancies and is responsible for approximately one-third of preterm deliveries. PPROM can lead to serious complications including preterm birth, infection (chorioamnionitis), umbilical cord prolapse, and placental abruption. Management involves balancing the risks of prematurity against the risks of infection, often including antibiotic prophylaxis, corticosteroids for fetal lung maturity, and close monitoring for signs of infection or labor.
Usage
Usage note: Distinguish from PROM (term premature rupture of membranes) which occurs at ≥37 weeks.
In Context
- "PPROM at 32 weeks required hospitalization for antibiotic therapy and fetal monitoring." — Admission note
- "The patient's PPROM was managed conservatively with bed rest and serial laboratory monitoring." — Obstetric care plan