maternal serum screening

Full Definition

A series of blood tests performed on pregnant women, typically during the first and second trimesters, to measure levels of specific proteins and hormones. These biomarkers are used in combination with maternal age and other factors to calculate risk probabilities for conditions such as Down syndrome, Edwards syndrome, and neural tube defects. Results are expressed as risk ratios or multiples of the median (MoM), requiring careful interpretation and patient counseling regarding screening versus diagnostic testing.

Usage

Usage note: Distinguish from diagnostic procedures when documenting patient counseling.

In Context

• "Maternal serum screening results indicated an increased risk requiring genetic counseling." — Prenatal care documentation
• "The patient declined maternal serum screening after extensive counseling." — Informed consent documentation