bladder preservation therapy
Multimodal treatment approach combining chemotherapy and radiation to treat muscle-invasive bladder cancer while preserving the bladder.
Full Definition
Bladder preservation therapy, also known as trimodality therapy, is an organ-sparing treatment approach for muscle-invasive bladder cancer that combines transurethral resection, concurrent chemoradiation therapy, and close surveillance. This approach offers an alternative to radical cystectomy for carefully selected patients with muscle-invasive disease. The treatment protocol typically involves initial transurethral resection followed by concurrent chemotherapy (often cisplatin-based) and external beam radiation therapy, with cystoscopic monitoring to assess response.
Usage
Usage note: Use 'preservation' not 'preserving' in formal contexts.
In Context
- "The patient opted for bladder preservation therapy rather than radical cystectomy." — Treatment planning note
- "Bladder preservation therapy achieved complete response in 70% of patients at 6 months." — Clinical trial report