Professional
Technical
IVT
Gleason score
Histologic grading system for prostate cancer aggressiveness based on tumor architecture.
Full Definition
A histopathologic grading system developed by Dr. Donald Gleason that evaluates prostate cancer based on the architectural patterns of cancer cells. The score ranges from 6 to 10, representing the sum of the two most common tumor patterns observed. Lower scores indicate well-differentiated, less aggressive tumors, while higher scores suggest poorly differentiated, more aggressive disease. The Gleason score is crucial for treatment planning and prognosis.
Usage
Usage note: Always capitalize 'Gleason' as it's named after Dr. Donald Gleason.
In Context
- "Pathology revealed adenocarcinoma with a Gleason score of 3+4=7." — Pathology report
- "The Gleason score remains the most important prognostic factor in prostate cancer." — Medical textbook
Also known as
Gleason grade
Don't confuse with
TNM staging
grade group