tumor burden assessment
Systematic evaluation of total disease volume and distribution to guide treatment selection in metastatic neuroendocrine tumors.
Full Definition
Tumor burden assessment represents a comprehensive evaluation of total disease volume, number of lesions, and anatomical distribution in patients with metastatic neuroendocrine tumors. This assessment influences treatment decisions between local therapies, systemic treatments, and multimodal approaches. Key components include hepatic tumor burden measurement, extrahepatic disease sites, and functional imaging findings. The evaluation helps stratify patients for different therapeutic options such as hepatic arterial therapies, peptide receptor radionuclide therapy, or systemic chemotherapy. Serial assessments also guide response evaluation and progression monitoring.
Usage
Usage note: Include both quantitative and qualitative aspects of disease distribution.
In Context
- "Comprehensive tumor burden assessment revealed predominant hepatic involvement suitable for arterial therapies." — Treatment planning
- "The extensive tumor burden assessment guided selection of systemic therapy over local interventions." — Multidisciplinary consultation