Gastrointestinal Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
pCR pCR
Pathological complete response indicating absence of viable tumor cells after neoadjuvant treatment.
HIPEC
A specialized surgical procedure combining tumor removal with heated chemotherapy delivered directly into the abdominal...
imatinib
A targeted therapy drug that inhibits specific protein kinases, primarily used to treat gastrointestinal stromal tumors...
jejunostomy
Surgical creation of an opening into the jejunum for feeding or decompression.
Kasai procedure
A surgical procedure to treat biliary atresia by creating drainage from the liver to the intestine when normal bile duct...
Klatskin tumor
A type of bile duct cancer arising at the confluence of the right and left hepatic ducts, also known as hilar cholangioc...
Kocher maneuver
A surgical technique involving mobilization of the duodenum and pancreatic head by dividing lateral peritoneal attachmen...
KRAS mutation
A genetic alteration in the KRAS gene commonly found in gastrointestinal cancers that affects treatment options.
Krukenberg tumor
Ovarian metastasis from gastrointestinal cancer, typically signet ring cell type.
Lauren classification
A histological classification system for gastric adenocarcinoma distinguishing intestinal, diffuse, and mixed types.
Lynch syndrome
Hereditary cancer syndrome causing predisposition to colorectal and other gastrointestinal malignancies due to mismatch...
malignant bowel obstruction
Intestinal blockage caused by primary gastrointestinal tumors or peritoneal metastases in advanced cancer patients.
Mallory-Weiss tear
A longitudinal mucosal laceration in the distal esophagus caused by sudden increase in intragastric pressure.
Margin status
The pathological assessment of surgical resection margins to determine completeness of tumor removal and predict recurre...
MDT
Multidisciplinary team meeting where specialists review complex cancer cases collaboratively.
Meckel's diverticulum
Congenital small bowel diverticulum that may contain ectopic gastric tissue and present with bleeding or obstruction.
mesenteric lymphadenopathy
Enlargement of lymph nodes within the mesentery, often indicating malignancy or inflammatory disease.
microsatellite instability
A molecular phenotype characterized by accumulated mutations in repetitive DNA sequences, indicating defective DNA misma...
mucinous adenocarcinoma
Subtype of adenocarcinoma characterized by abundant extracellular mucin production.
Murphy's sign
A clinical examination finding indicating gallbladder inflammation, characterized by abrupt cessation of inspiration due...
neoadjuvant therapy
Cancer treatment administered before the primary surgical intervention to shrink tumors and improve surgical outcomes.
octreotide scan
A nuclear medicine imaging technique using radiolabeled somatostatin analog to detect neuroendocrine tumors.
Pancreatic ductal adenocarcinoma
The most common form of pancreatic cancer arising from ductal epithelial cells, accounting for approximately 85% of case...
pancreatic ductal stricture
Narrowing of the main pancreatic duct that may indicate malignancy or benign inflammatory disease.
Pancreatic enzyme replacement therapy
Medical treatment with exogenous pancreatic enzymes to manage pancreatic exocrine insufficiency following surgery or dis...