Immunohistochemistry Panel
Also written as: IHC — Immunohistochemistry
A set of antibody-based stains used to identify specific proteins in tumor tissue for diagnostic classification.
Full Definition
An immunohistochemistry panel in neuro-oncology consists of multiple antibody-based stains applied to tumor tissue specimens to identify characteristic proteins that aid in accurate tumor classification. These panels typically include markers for glial differentiation, proliferation indices, and molecular characteristics that determine treatment approaches. The specific antibodies used vary by suspected tumor type, and results must be interpreted in conjunction with morphological features and molecular testing. Proper documentation includes both positive and negative staining patterns.
Usage
Usage note: Specify which markers were included when referencing immunohistochemistry panels in reports.
In Context
- "The immunohistochemistry panel confirmed glial fibrillary acidic protein positivity in the tumor cells." — Pathology report
- "An extended immunohistochemistry panel was performed to distinguish between primary and metastatic brain tumors." — Laboratory requisition