mastocytoma
Pronunciation: mas-to-sy-TOH-mah
A solitary lesion of mastocytosis presenting as a brown or red nodule that may blister when rubbed.
Full Definition
Mastocytoma is a solitary cutaneous lesion representing localized mastocytosis, most commonly occurring in infants and young children. It typically presents as a brown, red, or yellow nodule that may develop urticaria, blistering, or flushing when rubbed or traumatized (positive Darier's sign). Unlike systemic mastocytosis, solitary mastocytomas are generally benign and may resolve spontaneously during childhood. However, they require careful evaluation to exclude systemic involvement, particularly if multiple lesions are present.
Usage
Usage note: Document Darier's sign testing results and consider tryptase levels to evaluate for systemic disease.
In Context
- "The mastocytoma demonstrated a positive Darier's sign with urticaria upon stroking." — Physical examination finding
- "Baseline tryptase level was normal, consistent with localized mastocytoma without systemic involvement." — Laboratory results interpretation