vitiligo
Pronunciation: vit-ih-LYE-go
An autoimmune disorder causing progressive loss of melanocytes, resulting in well-demarcated white patches of skin depigmentation.
Full Definition
Vitiligo is an acquired autoimmune condition characterized by selective destruction of melanocytes, leading to circumscribed areas of complete depigmentation. In pediatric patients, vitiligo often presents with a symmetric distribution and may be associated with other autoimmune conditions including thyroid disease, alopecia areata, and type 1 diabetes. The condition can have significant psychological impact on children and adolescents, making early intervention and psychosocial support important components of comprehensive care.
Usage
Usage note: Document distribution pattern (focal, segmental, or generalized) when describing vitiligo.
In Context
- "The 10-year-old patient developed symmetric vitiligo patches on both hands over six months." — New patient evaluation
- "Wood's lamp examination enhanced the visibility of early vitiligo lesions on the child's face." — Diagnostic procedure note