gliomatosis cerebri
Pronunciation: glee-oh-mah-TOE-sis seh-REE-bry
A rare form of diffuse glioma characterized by extensive infiltration of multiple brain regions without forming a discrete mass.
Full Definition
Gliomatosis cerebri is a rare pattern of diffuse glial tumor growth characterized by extensive infiltration of multiple brain regions, typically involving at least three cerebral lobes, without forming a well-defined mass lesion. In pediatric patients, this condition presents unique diagnostic and therapeutic challenges due to its diffuse nature and the difficulty in obtaining representative tissue samples. The WHO classification has evolved, and this entity is now considered a growth pattern rather than a distinct tumor type.
Usage
Usage note: Current WHO classification considers this a growth pattern rather than a distinct entity.
In Context
- "MRI findings were consistent with gliomatosis cerebri showing T2 hyperintensity involving bilateral hemispheres." — Radiology report
- "Gliomatosis cerebri presents unique challenges in pediatric patients due to its extensive infiltrative nature." — Clinical guidelines