MIBG scan
Pronunciation: MY-big scan
Also written as: MIBG — Metaiodobenzylguanidine
Nuclear medicine imaging study using radiotracer to detect neuroblastoma and other neuroendocrine tumors.
Full Definition
MIBG (Metaiodobenzylguanidine) scan is a specialized nuclear medicine imaging technique that uses a radioactive tracer to detect neuroblastoma, pheochromocytoma, and other neuroendocrine tumors. The radiotracer I-123 or I-131 MIBG is taken up specifically by cells containing norepinephrine transporters, making it highly sensitive for neural crest tumors. MIBG scans are essential for neuroblastoma staging, assessing treatment response, surveillance for recurrence, and determining eligibility for MIBG therapeutic protocols. The scan requires specific patient preparation including thyroid blockade and discontinuation of certain medications that may interfere with uptake.
Usage
Usage note: Specify isotope used (I-123 vs I-131) and preparation requirements; distinguish from anatomic imaging.
In Context
- "MIBG scan demonstrated avid uptake in the primary abdominal mass and multiple skeletal sites." — Imaging report
- "Post-therapy MIBG scan showed complete resolution of previously noted abnormal uptake." — Treatment response evaluation