Intermediate
Technical
In the Industry Vocabulary Test
tumor markers
Biochemical substances measurable in blood or other body fluids that can indicate the presence or progression of certain pediatric cancers.
Full Definition
Tumor markers are biochemical substances produced by cancer cells or by the body in response to cancer that can be measured in blood, urine, or other body fluids. In pediatric oncology, important tumor markers include alpha-fetoprotein (AFP) for hepatoblastoma and germ cell tumors, beta-hCG for certain germ cell tumors, and catecholamines for neuroblastoma. These markers are used for diagnosis, monitoring treatment response, and detecting relapse.
Usage
Usage note: Specify which markers when discussing specific tumor types.
In Context
- "Serial tumor markers showed declining AFP levels following hepatoblastoma resection." — Treatment monitoring
- "Elevated tumor markers at diagnosis helped confirm the suspected germ cell tumor." — Diagnostic workup
Also known as
biomarkers
serum markers
Don't confuse with
inflammatory markers
prognostic factors